GI Masterclass: Advanced Perspectives in Gastrointestinal Health
Host Genetics | H pylori | Intestinal Permeability
In-person event | Utrecht

The gastrointestinal system is central to immune balance, metabolic regulation, and overall vitality, yet disruptions often remain unnoticed until systemic symptoms emerge. This one-day intensive explores Helicobacter pylori infection dynamics and eradication strategies within an integrative framework, alongside a detailed examination of intestinal permeability (“leaky gut”), including immune-mediated, microbiome-associated, metabolic and genetically influenced patterns.  

The training goes beyond the basics, exploring how combining host genetic insights with functional microbiome investigations can elevate precision in gut health assessment and intervention. With growing recognition of host-genetic variability in gut function, using the DNA Gut profile, we will also examine how polymorphisms affecting mucosal integrity, immune signaling, detoxification, and microbial interactions can predispose individuals to gastrointestinal dysfunction and influence clinical outcomes.

Participants will gain clinical insights into:
- Mechanistic models of mucosal barrier breakdown and repair, including genetic susceptibility factors
- Distinguishing functional drivers of intestinal permeability and how genetic variations may modify presentation and treatment response
- Interpretation of advanced stool and genetic testing in the context of host-microbiome-genetic interactions
- Evidence-informed treatment strategies to address H pylori, restore barrier integrity, modulate microbial balance, and personalise interventions based on genetic and functional findings

Our educators: 
Graeme Jones, Physiologist Clinical Development Director - Nordic Group

With extensive clinical experience from his own patient work, Graeme is deeply passionate about teaching and coaching medical professionals and health therapists in functional medicine and nutritional science. Over the past 20 years, Graeme has built a broad and in-depth expertise across medicine, fitness, rehabilitation, nutrition, and clinical research. His academic background includes qualifications in lifestyle medicine, nutritional physiology, nutrigenomics, and a bachelor’s degree in Sport, Health & Exercise. He has also worked extensively within concierge medicine and longevity, providing personalised healthcare solutions focused on optimising long-term health, performance, and disease prevention. Read more

Diana Siepmann, Functional Medicine Consultant Practitioner Support at Nordic Laboratories & dnalifeDiana Siepmann is a certified Functional Medicine Consultant with more than eight years of experience translating complex biology into clinically actionable insights. With an educational background and professional experience spanning hormone, gut and immune health, she has more recently applied this comprehensive knowledge to providing personalised support in (peri)menopause. A key aspect of this work is the optimisation of metabolic health, which has led to a particular interest in how gut function, microbial ecology and genetic variation interact to influence metabolic regulation - mechanisms that are highly relevant in this life stage but broadly applicable across patient populations. Through her analytical and educational approach, she supports physicians and other healthcare professionals by integrating functional testing and DNA-based insights to translate complex systems biology into practical, personalised strategies aimed at restoring long-term physiological resilience.

Practical
Date and times: 27 September 2026, 09:00-17:00
Location: Suits & Sundays, Plompetorengracht 18, 3512 CD Utrecht

Lunch and snacks are provided.

If you have any questions please email events@nordicgroup.eu